Ezzadein was born in 1934 in Dargazen neighborhood of Sulaymaniyah, the third child of his father and fourth child of his mother. When her mother divorced her first husband, she remarried Mullah Mustafa Safuat.
Ezzadein lived in an educated family; His grandfather, Haji Mullah Rasul, was a religious scholar during the South Kurdistan government and was listened to by the king and officials.
Haji Mullah Rasoul had five sons, all of whom were educated and religious teachers. Mullah Mustafa, Dr. Ezzadein 's father, lived a middle-class life in Sulaymaniyah and was constantly engaged in reading, especially Sufism.
Ezzadein studied with his father in the mosque of Haji Mullah Rasul Delezha. In 1939, he was admitted as a listener in Ghazi School. After half a year, he was admitted because he was a very good student and graduated first at the end of the year.
He went to secondary school and passed the bachelor's examination in ninth grade. Mustafa Safuat told him to go to Baghdad to continue his studies and study at the Sharia College, as it is both an academic education and you will remain a mullah.
After going to Baghdad, he became a student of Sharia College, but because of his involvement in political activities, he did not complete the first year of Sharia and was expelled. Then he returned to Sulaymaniyah and the following year he went to the fourth grade of the science department. There was no literature department in Sulaymaniyah at that time, it was opened the following year. One of his teachers, Musa, asked him to enter the literature department in the fifth grade of night school. After completing the fifth grade, he went to Baghdad.
In 1951, he was admitted to the teachers' institute. In 1952, he participated in the uprising in Baghdad. He was wounded and later expelled from college. He returned to Sulaymaniyah and was employed as a worker in the Malaria Directorate.
Later, his father appointed him as a primary school teacher in Qaladze, but he was transferred to Sulaymaniyah for political reasons, then to Qamchugha, where he was engaged in political work. They returned him later to Sulaymaniyah.
He continued his studies at the College of Arts in Syria and completed grades 2-3 of the Arabic Department of Arts. He returned to Baghdad until the July 14, 1958 revolution and was appointed to the third grade of the teachers' college. He then graduated and was employed in the Kurdish Education Directorate in Baghdad. At that time, Abdul Karim Qasim began sending students to the Soviet Union on behalf of the state. Ezzadein Mustafa Rasoul was one of the students who went to the Soviet Union.
After completing his language studies, he went to Baku with Kamal Mazhar and Nasrin Fakhri. On June 24, 1963, he received his doctorate.
In 1965, he returned to Kurdistan and went to the mountains and became a Peshmerga of the Iraqi Communist Party. However, after a year in Barzani's headquarters, on 26/12/1966, with the efforts of Mullah Mustafa Barzani, he became a lecturer at Baghdad University and was appointed in the Kurdish department.
In 1979, he returned to Moscow, where he continued his studies and received his doctorate and professorship.
In 1992, he became a member of the first parliament of the Kurdistan Region on the list of Patriotic Union of Kurdistan but as an independent candidate.
Ezzadein Mustafa is one of the founders of the Kurdish Writers Union. The founding committee consisted of 11 people. In 1969, they received their license and Jamal Baban was appointed chairman of the founding committee. However, after the return of the mountain writers after the March 11 statement, this committee was dissolved and elections were held in Baghdad. Ezzadein was elected president of the Kurdish Writers Union with 63 votes.
In 1974, a congress of the Kurdistan Writer's Union was held in Erbil. Sayda Saleh Yousfi was elected as the president of the congress. Ezadin was his deputy. He later continued his cultural work within this organization. After the 1991 uprising, he worked more freely.
Dr. Ezzadein has played an important role in the Writers Union, both in solving problems and in activities, especially in publishing the magazine of the Writers Union.
In 2009, Dr. Ezzadein Mustafa received an Award for Personality of the Year in Literature.